1- RnD, Containment, Cloning, Warden's office (4)
Destroying cloning puts a huge hamper on things, especially with the Revivability update in the works, and destroying RnD makes it a huge bother to rebuild it, unless they remember the boards in tech storage (I'd say to steal them while you're at it, but if we're limiting ourselves to bombs, then oh well). Warden's office is in a prime spot to hamper security. Breaches the hallways, breaches the Armory, breaches the locker room. And releasing the engine is basically ten shuttle calls on it's own. While you could simply bomb the containment to fulfill that goal, the Tesla/Singu might bugger off into space, and there's the very real possibility of Admins just GOATing it.
2- RnD, Cloning, the Engine's SMESes, Warden's Office, Tech Storage (5)
RnD, Cloning and the Warden's Office for the same reasons above, but this time removing Tech Storage too. With no power charging the APCs and the surrounding areas being screwed up, chaos is but assured, especially with mass bombings.
3- RnD, Cloning, Cargo (Hitting both the cargo computers + mining ORM), Warden's Office, Bridge (5)
Same as the above, but hitting Cargo to cut off supplies being sent to the station, and the bridge as well to cause more mayhem.